See ratings and reviews when you sign up for an account.

Comparison of Quantiferon-TB Gold Assay With Tuberculin Skin Testing in the Assessment of Latent Mycobacterium Tuberculosis Infection in Patients Candidate to Treatment or Treated With TNF? Antagonists

This study is currently Recruiting

June 2007 By Ospedale L. Sacco ? Polo Universitario

First Recieved on June 25, 2007

Last Updated on June 25, 2007

Sponsor: Ospedale L. Sacco ? Polo Universitario
Information provided by: Ospedale L. Sacco ? Polo Universitario
Identifier: NCT00491933


The purpose of this study is to evaluate the value of Quantiferon-TB Gold (QFT-G) assay in the screening for latent tuberculosis infection (LTBI) in rheumatologic patients due to start or on treatment with TNF? antagonists. The results of QFT-G will be compared to tuberculin skin testing (TST) and correlated to clinical and demographic data. The study hypothesis is that the inclusion of QTF-G in the screening strategy will allow a more accurate assessment of LTBI infection.

Study Type: Interventional
Study Design: Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic


Ages Eligible for Study:18 Years
Genders Eligible for Study:Both
Accepts Healthy Volunteers:No

Inclusion Criteria: - Patients with rheumatological diseases being evaluated for treatment with TNF? antagonists or on treated with TNF? antagonists Exclusion Criteria: - Unable to sign informed consent - Known hypersensitivity to tuberculin


  • Investigator: Marco Antivalle, MD - Principal Investigator - Ospedale L. Sacco - Polo Universitario, Milano, Italy


  • Rheumatology Unit, Ospedale L. Sacco Polo Universitario

    Milano, 20157 Italy

Conditions related to this trial:

Disclaimer: The list and ratings above are for informational purposes only, and is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. The goal of the information is to provide you with a comprehensive view of all available treatments, but should not be construed to indicate that use of any one treatment is safe, appropriate, or effective for you. Decisions about use of a new treatment, or about a change in your current treatment plan, should be in consultation with your doctor or other healthcare professional.