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Effectiveness of a Complementary and Integrative Therapy in Diabetic Neuropathy Patients.

This study is currently Recruiting

January 2011 By Universit?t Duisburg-Essen

First Recieved on February 14, 2011

Last Updated on March 2, 2011

Sponsor: Universit?t Duisburg-Essen
Information provided by: Universit?t Duisburg-Essen
Identifier: NCT01296308


Despite the long tradition of complementary and alternative medicine (CAM) therapies there are hardly any interventional trials on type 2 diabetes mellitus. Hence this pilot study aims to investigate the influence of a two weeks integrative inpatient therapy on the quality of life in 50 patients suffering from diabetic neuropathy. Integrative treatment includes aspects of conventional and traditional European and Chinese medicine, mind-body medicine, physical therapy and lifestyle modification (nutrition advices, stress management and exercise training). The observational design intends four measurement points: tree months before (T0), directly before (T1), directly after treatment (T2) and three months follow-up (T3). The subjective evaluation of the neuropathy-related quality of life was combined with neurophysiologic instruments (QST), to measure neuropathic symptoms. Also pain intensity, locus of control, interpretation of illness, coping style, anxiety/depression, life satisfaction and several biomarkers (HbA1c, ABI, WHR and BMI) are measured. In addition a qualitative interview should give a view to patient perspective of therapy process.

Study Type: Observational
Study Design: Observational Model: Cohort, Time Perspective: Prospective


Ages Eligible for Study:18 Years
Genders Eligible for Study:Both
Accepts Healthy Volunteers:No

Inclusion Criteria: - over 18 years old - diabetes mellitus type 2 Exclusion Criteria: - diabetes mellitus type 1 - pregnancy - oncologic diseases - systemic neurological diseases - other induced neuropathy (radicular, s/p alcohol abuse, chemotherapy-induced) - other severe psychiatric or somatic comorbidity


  • Investigator: Gustav J. Dobos, Prof. MD - Principal Investigator - University of Duisburg-Essen


  • Kliniken Essen-Mitte

    Essen, NRW 45276 Germany

Conditions related to this trial:

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