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Effects of Treated and Untreated Allergic Rhinitis on Mood, Cognitive Functions and Actual Driving Performance

This study is currently Recruiting

March 2011 By Maastricht University Medical Center

First Recieved on March 17, 2011

Last Updated on March 17, 2011

Sponsor: Maastricht University Medical Center
Information provided by: Maastricht University Medical Center
Identifier: NCT01318681


This study investigates the effects of Allergic Rhinitis (AR) on driving ability and memory functions. Our group has previously shown that patients suffering from AR symptoms perform less well on tasks requiring sustained attention compared to non symptomatic controls. Car driving is a typical behavior that is susceptible for changes in sustained attention and might therefor become worse under conditions when patients suffer from AR symptoms. We will compare the driving performance of untreated, symptomatic AR patients with the performance of symptomatic patients that have been treated with either a systemic AR medication (a pill) or a topical medication (nasal spray)

Study Type: Interventional
Study Design: Allocation: Randomized, Endpoint Classification: Pharmacodynamics Study, Intervention Model: Crossover Assignment, Masking: Double Blind (Subject, Investigator)


Ages Eligible for Study:21 Years
Genders Eligible for Study:Both
Accepts Healthy Volunteers:Accepts Healthy Volunteers

Inclusion Criteria: - Healthy volunteers known with Seasonal Allergic Rhinitis - Experienced drivers holding a license - 21- 45 years of age Exclusion Criteria: - Asthma or other chronic illness - current psychoactive medication - History of drug abuse



  • Maastricht University

    Maastricht, Limburg 62ooMD Netherlands

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