Abilify, also known by the generic name aripiprazole, is an antipsychotic drug. While it is typically used to treat schizophrenia, a mental illness, Abilify is sometimes also used to manage and prevent chronic migraine headaches, depression, bipolar disorder, and autistic disorder in children. Abilify affects the behaviors of naturally-occurring substances (dopamine and serotonin) in the brain to control chronic migraines and mental health problems. Abilify also helps to manage aggressive behaviors, anger, and irritability. Side effects of Abilify can include feeling dizzy or nervous, drowsiness, increase in appetite and weight, joint pain, and digestive problems. In some cases, it can take up to six to 12 weeks for Abilify to be effective.