Condition: Argininosuccinic Aciduria

Use these Health Check-up tools to learn more

How are people coping?

Who else is affected?

Members in the community range from 2 to 6 years old

See them

How are you feeling?

About Argininosuccinic Aciduria

Argininosuccinic aciduria is a rare inherited disorder characterized by deficiency or lack of the enzyme argininosuccinate lyase (ASL). Argininosuccinate lyase is one of six enzymes that play a role in the breakdown and removal of nitrogen from the body, a process known as the urea cycle. The lack of this enzyme results in excessive accumulation of nitrogen, in the form of ammonia (hyperammonemia), in the blood. Affected infants may experience vomiting, refusal to eat, progressive lethargy, and coma. Argininosuccinic aciduria is inherited as an autosomal recessive trait.

The urea cycle disorders are a group of rare disorders affecting the urea cycle, a series of biochemical processes in which nitrogen is converted into urea and removed from the body through the urine. Nitrogen is a waste product of protein metabolism. Failure to break down nitrogen results in the abnormal accumulation of nitrogen, in the form of ammonia, in the blood.

Most effective Argininosuccinic Aciduria treatments reported by our membersLogin to add your rating >

  • How effective?
    How common?
    Description
  • No treatments have been listed

Most severe Argininosuccinic Aciduria symptoms reported by our membersLogin to add your rating >

  • How severe?
    How common?
    Description
  • There have been no symptoms added by our members for this condition yet.

Connect with people like you when you join!

People near you with Argininosuccinic Aciduria

Treatment Symptom Age Gender

Read what others are saying about Argininosuccinic Aciduria

There are no comments yet. Be the first
There are no comments yet. Be the first

Join the conversation

You must be a member to join the conversation.

Join now for FREE to learn and share about your condition with other members

See questions people are asking. Or ask your own

There are no topics for this condition yet

Related conditions

  • There is currently no data available

Active Clinical Trials

advertisement
V2012.311.925.327
Last updated on Jul 02 2018 at 05:13
Disclaimer: The list and ratings above are for informational purposes only, and is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. The goal of the information is to provide you with a comprehensive view of all available treatments, but should not be construed to indicate that use of any one treatment is safe, appropriate, or effective for you. Decisions about use of a new treatment, or about a change in your current treatment plan, should be in consultation with your doctor or other healthcare professional.