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Condition: Hageman Factor Deficiency

Home > Publications > Condition: Hageman Factor Deficiency

Hageman factor deficiency, also known as factor XII deficiency, is a rare genetic blood disorder that causes prolonged clotting (coagulation) of blood in a test tube without the presence of prolonged clinical bleeding tendencies. It is caused by a deficiency of the Hageman factor (factor XII), a plasma protein (glycoprotein). Although it is thought that factor XII is needed for blood clotting, when it is deficient, other blood clotting factors tend to compensate for its absence.

This disorder is thought to be benign and usually presents no symptoms (asymptomatic); it is usually only accidentally discovered through pre-operative blood tests that are required by hospitals. Of substantial recent interest is the role of antibodies to Factor XII in recurrent pregnancy losses.

Most effective Hageman Factor Deficiency treatments reported by our members

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Disclaimer: The list and ratings above are for informational purposes only, and is intended to supplement, not substitute for, the expertise and judgment of your physician, pharmacist or other healthcare professional. The goal of the information is to provide you with a comprehensive view of all available treatments, but should not be construed to indicate that use of any one treatment is safe, appropriate, or effective for you. Decisions about use of a new treatment, or about a change in your current treatment plan, should be in consultation with your doctor or other healthcare professional.

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