Severe chronic neutropenia (SCN) is a rare blood disorder characterized by abnormally low levels of certain white blood cells (neutrophils) in the body (neutropenia). Neutrophils play an essential role in fighting bacterial infections by surrounding and destroying invading bacteria (phagocytosis).
Symptoms associated with severe chronic neutropenia include recurring fevers, mouth sores (ulcers), and/or inflammation of the tissues that surround and support the teeth (periodontitis). Due to low levels of neutrophils, affected individuals may be more susceptible to recurring infections that, in some cases, may result in life-threatening complications.
SCN may last for months or years and can affect both children and adults. Clinicians recognize four forms of the disorder: congenital, cyclical, idiopathic, and autoimmune neutropenia. The term idiopathic is used when severe chronic neutropenia occurs for unknown reasons.
Most effective Neutropenia, General treatments reported by our members
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Most severe Neutropenia, General symptoms reported by our members
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