Von Willebrand disease (vWD) is an inherited bleeding disorder resulting in prolonged bleeding. Certain specialized proteins called clotting factors aid the blood to clot. Individuals with von Willebrand disease have a defect in or deficiency of one of these proteins known as von Willebrand factor. They may also have low levels of an additional factor known as factor VIII.
Deficient or defective von Willebrand factor results in improper functioning of platelets, specialized red blood cells that mass together to form clots to stop bleeding. In individuals with von Willebrand disease, platelets do not stick to holes in blood vessels and bleeding is prolonged.
Von Willebrand disease is inherited as an autosomal dominant or recessive trait.
Most effective Von Willebrand Disease treatments reported by our members
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Most severe Von Willebrand Disease symptoms reported by our members
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